Cognitive impairment, Metabolic Syndrome and Stress

I have created an extremely comprehensive diagram exposing the link between chronically elevated stress (>6 months – 1 year) and blood sugar imbalances, insulin resistance and the symptoms of the Metabolic Syndrome, impaired cognitive functions and oestrogen dominance disorders, taking into consideration the emotional status, and psychological responses. 
 The effect of high blood Cortisol levels have many implications on health and disease expression, and it all starts with out-of-control stress response or Chronic Stress.

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References:
Lupien, SJ. et al. (1998). Cortisol levels during human aging predict hippocampal atrophy and memory deficits. Nature Neuroscience. 1, pp. 69–73.
Csernansky, JG. et al. (2006). Plasma Cortisol and Progression of Dementia in Subjects With Alzheimer-Type Dementia. American Journal of Psychiatry. 163, pp. 2164–2169.
Jokinen, J. Nordström, P. (2009). HPA axis hyperactivity and cardiovascular mortality in mood disorder inpatients. Journal of Affective Disorders. 116 (1–2), Pages 88–92.
Buckley, TM. Schatzberg, AF. (2005). On the Interactions of the Hypothalamic-Pituitary-Adrenal (HPA) Axis and Sleep: Normal HPA Axis Activity and Circadian Rhythm, Exemplary Sleep Disorders. The Journal of Clinical Endocrinology & Metabolism. 90 (5), pp. 3106–3114.